BULGARIAN NMR CENTRE

Website

Research interests

Development and application of advanced NMR approaches:

Liquid phase NMR spectroscopy
- Structural analysis and stereochemistry of synthetic organic compounds
- Molecular mobility - classical dynamic NMR for the investigation of tautomeric and conformational equilibria.
- Diffusion NMR spectroscopy - investigation of supramolecular complexes, processes of self-aggregation, particle size determination in colloidal systems, analysis of complex mixtures.
- Chemical profiling and metabolic analysis of extracts of plant origin
- Analysis of food and natural products
- NMR spectroscopy with in situ irradiation

Solid state NMR spectroscopy
- Structure of mesoporous silicates and zeolites
- Organic-inorganic hybrid materials

NMR spectroscopy of soft materials - Polymeric (hydro)gels
- Extracts of medicinal and aromatic plants

LABORATORY MEMBERS

Head:

Prof. Dr. Pavletta Shestakova


02 9606 136
209
psd@orgchm.bas.bg
Name Room Phone -mail*
Prof. Pavletta Shestakova, PhD, Head 209 136 psd
Prof. Nikolay Vassilev, PhD 112 172 niki
Prof. Svetlana Simova, DSc 104 140 sds
Assist. Prof. Alexander Kantardjiev, PhD 117 189 alexkant
Assist. Prof. Miroslav Dangalov, PhD 112 172 m.dangalov
Assist. Prof. Yavor Mitrev, PhD 106 146 yavor
Dessislava Gerginova, Phd student 103 120 dpg

Projects

Financing organization: National science fund, Ministry of education and science Project title: In situ irradiation NMR spectroscopy in the design of new functional materials (LED-NMR) Coordinator of the research team: Prof. Dr. Nikolay Vassilev Webpage

Financing organization: Ministry of education and science, Project title: National Scientific Infrastructure: Distributed infrastructure of centers for synthesis and characterization of new materials and conservation of archeological and ethnographic artefacts (INFRAMAT) Coordinator of the research team (IOCCP-BAS): Prof. Dr. Pavletta Shestakova Webpage

Selected group publications(Q1)

2019

Eur. J. Pharm. Biopharm,
142,
460-472
Verapamil delivery systems on the basis of mesoporous ZSM-5/KIT-6 and ZSM-5/SBA-15 polymer nanocomposites as a potential tool to overcome MDR in cancer cells
Bioorg. Chem.,
90,
103028
Discovery of novel indole-based aroylhydrazones as anticonvulsants: Pharmacophore-based design
J. Mol. Liq.,
292,
111392
Tautomerism in folic acid: Combined molecular modelling and NMR study
Angew. Chem. Int. Ed.,
58,
5
Reactive Dimerization of an N-Heterocyclic Plumbylene: C-H Activation with PbII
Bioorg. Chem.,
85,
487-497
Anti-enteroviral activity of new MDL-860 analogues: Synthesis, in vitro/in vivo studies and QSAR analysis
Polym. Int.,
68,
9
Polyzwitterionic hydrogels as wound dressings with enzymatic debridement functionality for highly exuding wounds
ChemSusChem, 11,
10,
1612-1616
Going Beyond the Limits of the Biorenewable Platform: Unprecedented Sodium Dithionite Promoted Stabilization of 5-Hydroxymethylfurfural
Food and Chemical Toxicology, 111,
605-615
New iridoids from Verbascum nobile and their effect on lectin-induced T cell activation and proliferation
Applied Catalysis A: General, 560,
119-131
Efficient solid acid catalysts based on sulfated tin oxides for liquid phase esterification of levulinic acid with ethanol.