Изследователска дейност

Разработване и приложение на съвременни ЯМР спектрални подходи:

• ЯМР спектроскопия в течна фаза:
- Структурен анализ и стереохимия на синтетични органични съединения.
- Молекулна подвижност – класически динамичен ЯМР за изследване на тавтомерни и конформационни равновесия.
- Дифузионна ЯМР спектроскопия – изследване на надмолекулни комплекси, процеси на самоагрегиране и размери на частици в колоидни системи, анализ на сложни смеси.
- Химично профилиране и метаболомен анализ на екстракти от растителен произход
- Анализ на храни и природни продукти
- ЯМР спектроскопия с in situ облъчване

• ЯМР спектроскопия в твърда фаза:
- Структура на мезопорести силикати и зеолити
- Органични-неорганични хибридни системи

• ЯМР спектроскопия на меки материали:
- Полимерни (хидро)гелове
- Екстракти от медицински и ароматни растения

ПЕРСОНАЛ

Ръководител:

проф. д-р Павлета Шестакова

02 9606 136

209

Pavletta.Shestakova@orgchm.bas.bg

Име	Стая	Телефон	Е-поща*
проф. д-р Павлета Шестакова, ръководител	209	136	Pavletta.Shestakova
проф. д-р Николай Василев	112	172	Nikolay.Vassilev
проф. дн Светлана Симова	104	140	Svetlana.Simova
доц. д-р Явор Митрев	106	146	Yavor.Mitrev
гл. ас. д-р Александър Кантарджиев	117	189	Alexander.Kantardjiev
гл. ас. д-р Десислава Гергинова	103	120	Dessislava.Gerginova
гл. ас. д-р Мирослав Дангалов	112	172	Miroslav.Dangalov
техник-химия Пламен Чорбаджиев	103	120
Асоциирани членове
доц. д-р Божанка Михова	103

*Електронната поща се образува след добавяне на '@orgchm.bas.bg' към името

Текущи Проекти

Публикации (Q1)

2021

Int. J. Mol. Sci.,
22,
1759

Biotechnologically-Produced Myconoside and Calceolarioside E Induce Nrf2 Expression in Neutrophils

Algal Res.,
60,
102538

Immunomodulating polysaccharide complexes and antioxidant metabolites from Anabaena laxa, Oscillatoria limosa and Phormidesmis molle

Foods,
10,
997

A Preliminary Study of Chemical Profiles of Honey, Cerumen, and Propolis of the African Stingless Bee Meliponula ferruginea

Nanomaterials,
11,
2831

CO2 Adsorption on Modified Mesoporous Silicas: The Role of the Adsorption Sites

Molecules,
26,
5888

In Vitro Multiplication and NMR Fingerprinting of Rare Veronica caucasica M. Bieb

J. Mol. Liq.,
335,
116287

Neutral organophosphorus ligands as a molecular lab for simultaneous detecting of Ag(I) ions

Dyes Pigm.,
195,
109739

7-OH quinoline Schiff bases: are they the long awaited tautomeric bistable switches?

Phys. Chem. Chem. Phys.,
23,
13760-13767

А single isomer rotary switch demonstrating anti-Kasha behaviour: Does acidity function matter?

Organometallics,
40,
578–590

1,2-Disubstituted Planar Chiral Ferrocene Derivatives from Sulfonamide-Directed ortho-Lithiation: Synthesis, Absolute Configuration, and Chiroptical Properties

Molecules,
26,
7694

Hydrodemethoxylation/Dealkylation on Bifunctional Nanosized Zeolite Beta

Pharmaceutics,
13,
2025

PEG-Modified tert-Octylcalix[8]arenes as Drug Delivery Nanocarriers of Silibinin

Molecules,
26,
6865

Chiral Aminoalcohols and Squaric Acid Amides as Ligands for Asymmetric Borane Reduction of Ketones: Insight to In Situ Formed Catalytic System by DOSY and Multinuclear NMR Experiments

Molecules,
26,
3576

Selective Production of Phenol on Bifunctional, Hierarchical ZSM-5 Zeolites

Micropor. Mesopor. Mat. ,
323,
111203

Hybrid catalyst with combined Lewis and Bronsted acidity based on ZrIV substituted polyoxometalate grafted on mesoporous MCM-41 silica for esterification of renewable levulinic acid

Comput. Mater. Sci.,
117,
109570

Chercher de l'eau: The switching mechanism of the rotary switch ethyl-2-(2-(quinolin-8-yl)hydrazono)-2-(pyridin-2-yl)acetate

Molecules,
25,
4687

NMR Profiling of North Macedonian and Bulgarian Honeys for Detection of Botanical and Geographical Origin

J. Photochem. Photobiol. A,
396,
112555

Cationic amino acids linked to Zn(II) phthalocyanines for photodynamic therapy: Synthesis and effects on physicochemical properties

Molecules,
25,
3987

Synthetic Analogues of Aminoadamantane as Influenza Viral Inhibitors—In Vitro, in Silico and QSAR Studies

Molecules,
25,
3410

Veronica austriaca L. extract and arbutin expand mature double TNF-alpha/IFN-gamma neutrophils in murine bone marrow pool

Amino acids,
52,
1559–1580

Synthetic analogues of memantine as neuroprotective and influenza viral inhibitors: in vitro and physicochemical studies

J. Mater. Sci,
28,
13799–13814

Fluoride etching of AlZSM-5 and GaZSM-5 zeolites

Eur. J. Pharm. Biopharm,
142,
460-472

Verapamil delivery systems on the basis of mesoporous ZSM-5/KIT-6 and ZSM-5/SBA-15 polymer nanocomposites as a potential tool to overcome MDR in cancer cells

Bioorg. Chem.,
90,
103028

Discovery of novel indole-based aroylhydrazones as anticonvulsants: Pharmacophore-based design

J. Mol. Liq.,
292,
111392

Tautomerism in folic acid: Combined molecular modelling and NMR study

Angew. Chem. Int. Ed.,
58,
5

Reactive Dimerization of an N-Heterocyclic Plumbylene: C-H Activation with PbII

Bioorg. Chem.,
85,
487-497

Anti-enteroviral activity of new MDL-860 analogues: Synthesis, in vitro/in vivo studies and QSAR analysis

Polym. Int.,
68,
9

Polyzwitterionic hydrogels as wound dressings with enzymatic debridement functionality for highly exuding wounds

ChemSusChem, 11,
10,
1612-1616

Going Beyond the Limits of the Biorenewable Platform: Unprecedented Sodium Dithionite Promoted Stabilization of 5-Hydroxymethylfurfural

Food and Chemical Toxicology, 111,
605-615

New iridoids from Verbascum nobile and their effect on lectin-induced T cell activation and proliferation

Applied Catalysis A: General,
560,
119-131

Efficient solid acid catalysts based on sulfated tin oxides for liquid phase esterification of levulinic acid with ethanol.

Апаратура